Dr. K.Sobha



faculty

Associate Professor in Environmental Sciences

Date of Birth: 12.01.1964

Date of Joining: 01.10.2007

Teaching experience: 25+ years

Research experience: 16+ years

Other Qualifications:
  1. Qualified CSIR-UGC Joint JRF examination in March, 1988 and was awarded CSIR Fellowship (JRF & SRF) from October 1988 to September 1993.
  2. Qualified GATE examination in Life Sciences in February, 2003 with a Percentile of 90.4.
  3. Qualified in JNU - Entrance examination for admission into M. Tech. and Joined M. Tech. (Biotechnology) program with the student fellowship at Anna University.

Education

  • Ph. D. in the faculty of Life sciences, Nagarjuna University, in the year 1995.
  • M.Tech. in Biotechnology (Gold Medalist) from Anna University in the year 2005
  • M.Sc. and M. Phil. In Zoology from Andhra University (1988) and Nagarjuna University (1992)
  • M. Ed. From Annamalai University (Distance Education) in the year 1993.

Experience
Academic

  • Presently working as Associate Professor in Environmental Sciences, Department of Mathematics and Humanities, since 8th June 2015.
  • Worked as Associate Professor in the Department of Biotechnology, RVR & JC College of Engineering from 1st October 2007 to 6th May, 2015. (ANU Selection)
  • Joined as Senior Lecturer in the Department of Biotechnology, Bapatla College of Engineering in June, 2005 and was Promoted as Assistant Professor in the same Department with effect from 1st August, 2006. (ANU Selection).
  • Worked as Post Graduate Teacher in Kendriya Vidyalaya Sangathan from 1994 to 2003.
  • Worked as Teaching Assistant in the Department of Zoology for M. Sc. (Zoology) and M.Sc. (Environmental Sciences) for one academic year i.e., 1993 to 1994.
  • Taught M.Sc. (Zoology) students at Acharya Nagarjuna University during the period from October 1988 to September 1993.
  • Worked as Part-time Lecturer in Zoology at GVR & S Degree College for Girls and Siddhartha College for Boys for one academic year during 1988.
Research
  • CSIR - SRF, Zoology, Acharya Nagarjuna University, Guntur, 1990-1993
  • CSIR - JRF, Zoology, Acharya Nagarjuna University, Guntur, 1988-1990

Research Interests

  1. Molecular genetics of Diseases
  2. Industrial Biotechnology
  3. Genetic Engineering
  4. Protein Engineering
  5. Aquaculture
  6. Neuroendocrinology
National Seminars / Conferences Organized :
  1. Convener for the three day AICTE sponsored National Seminar on " 3D - Structure determination of drug molecule, molecular modeling and drug design" during 15th to 17th April, 2010 and delivered theme lecture on the topic "Molecular modeling and Drug design" (Published in the Proceedings).
  2. Program Co-ordinator for a one day state level work shop for faculty, organized on the theme "Environmental Studies: Innovative Teaching Methodologies" by the department on 3rd October 2016. Prof. R. Rajagopalan, a retired professor from IITM was the resource person. The program was organized in association with Oxford University Press and 49 faculty members from various degree and engineering colleges of the state participated.
National / International Symposia / Conferences attended:
  1. Dr. K. Sobha, Assistant Professor, National Workshop on "Design of Experiments and Operational Research" organized by Department of Statistics, Acharya Nagarjuna University, Guntur (under SAP) on 8th and 9th December, 2011.
  2. Dr. K. Sobha, Assistant Professor, "UGC, APPCB & APCOST sponsored National Seminar on "Youth towards New Trends in Biotechnology" organized by Maris Stella College, Vijayawada on 26th and 27th August, 2011.
  3. International Conference on Biodiversity and Aquatic Toxicology, organised by the Department of Zoology, Acharya Nagarjuna University during 12th to 14th February, 2011.
  4. State Level Conference on Research Methodology in Animal Sciences, organized by PR degree and PG college, Kakinada during 29th and 30th November, 2010.
  5. International Symposium on Emerging Trends in Biomedical and Nanobiotechnology: Relevance to Human Health organized by the Departments of Biotechnology and Nanotechnology at Acharya Nagarjuna University during 19th - 21st December 2009.
  6. National Seminar on Recent Trends in Life Sciences for Human Welfare - Organized at A.C. College, Guntur - 11th and 12th September, 2009.
  7. National Seminar on Tourism - A Catalyst in Economic Development - Organized at A.C. College, Guntur- 24th & 25th October, 2008.
  8. National Conference on Stem Cell Research - organized by the Department of Biotechnology, Acharya Nagarjuna University during 15th - 16th December, 2006.
  9. National Symposium on Recent Trends in Biochemistry-organized by the department of Biochemistry at T.J.P.S. College, Guntur - 22nd December 2006.
  10. International Symposium on Frontiers in Genetics and Biotechnology - Retrospect & Prospect: organized by Department of Genetics and Biotechnology, Osmania University & Hyderabad - 500 007; 8th to 10th January, 2006.
  11. 31st Annual Conference of the Indian Immunology Society " Trends in Infection Biology" , December 2004: Organized by the Centre for Biotechnology, Anna University, Chennai.

(Regional: 1; National: 7; International: 3)


Posters Presented:
  1. Dr. K. Sobha, Associate Professor and Y. Prem Sai, "Prospectives of Stem cell therapy in addressing the problems of male and female infertility and assuring every couple of their own biological child", Organized jointly by KIMS Foundation and Research Centre (KFRC) and CIENCIA Pvt. Ltd. on 23rd February, 2014.
  2. Dr. K. Sobha, Assistant Professor, "Nanoworms - Anti-Cancer Missiles", International Symposium on Emerging Trends in Biomedical and Nanobiotechnology: Relevance to Human Health(ISEBN-2009), Organized jointly by Department of Biotechnology and Department of Nanotechnology, Acharya Nagarjuna University, Guntur during 19th - 21st December, 2009.
  3. Dr. K. Sobha, Assistant Professor, "A study on Flavonoids as Aromatase Inhibitors Using QSAR Analysis", International Symposium on Emerging Trends in Biomedical and Nanobiotechnology: Relevance to Human Health(ISEBN -2009), Organized jointly by Department of Biotechnology and Department of Nanotechnology, Acharya Nagarjuna University, Guntur during 19th - 21st December, 2009.
  4. Molecular characterization of Clotting factors in Crustaceans - K. Sobha & V. Murugan; P-II:28; P. No. 69, Dt. 08.01.2006: at International Symposium on Frontiers in Genetics and Biotechnology - Retrospect & Prospect: organized by Department of Genetics and Biotechnology, Osmania University & Hyderabad - 500 007; 8th to 10th January, 2006.
Papers Presented at National Seminars/Symposia:
  1. Ratna Kumari A and Sobha K. Removal of lead and copper by adsorption with the renewable biopolymer composites of Chitosan (A. bisporus) and Egg shells (Gallus domesticus and Dromaeus novaehollandiae)/Feathers (Dromaeus novaehollandiae): A Comparative Study. 11th Asia Pacific Chitin and Chitosan Symposium held at Kochi, Kerala during 28th -30th September, 2016.
  2. K. Sobha. "A Saga of Technology And Innovation For Progress In 'Make In India' Mission" in the national Seminar on "March to Make in India through Engineering Advancements" organized by the department of Mechanical Engineering, RVR & JC College of Engineering, Guntur, Andhra Pradesh during 29th-30th September, 2016.
  3. Mahendra Kumar Verma and K. Sobha, "An in silico approach to resolve synovial inflammation by inhibiting Wnt signaling via post-translational modifications: phosphorylation and S-nitrosylation", International conference on Scenario of Biotechnology in 21st Century, Organized by School of Biotechnology (Silver Jubilee Celebrations), Devi Ahilya University, Indore, India during March 10-12, 2016.
  4. K. Sobha. "Sequence Alignments" in "Evolutionary Computing: An Intelligent Problem Solving for Science and Engineering Applications" - A two day national workshop organized by the department of computer applications at RVR & JC College of Engineering, Guntur, Andhra Pradesh, India during 27th - 28th November, 2015.
  5. K. Sobha, Assistant Professor, P. Dheeraj, M. Venu Madhavi and T. Priyanka, "Strategies for Effective Management of Anxiety Disorder - A Life Style Disease. International Symposium on "Innovation in Free Radical Research and Experimental Therapeutics", and 5th annual convention of Association of Biotechnology and Pharmacy conducted by Department of Biotechnology, Karunya University, Coimbatore during December 7-9, 2011.
  6. Sobha, 2009. Diabetic Retinopathy - Causes and Drug Intervention: National Seminar on Recent Trends in Life Sciences for Human Welfare - Organized at A.C. College, Guntur - 11th and 12th September, 2009.
  7. Sobha K., 2008. Promotion of Ecotourism - A Vital Need of the Society: National Seminar on Tourism - A Catalyst in Economic Development - Organized at A.C. College, Guntur- 24th & 25th October, 2008.
  8. Sobha et al., 2006. Synthetic Anti-microbial Peptide - Design and Cloning: National Symposium on Recent Trends in Biochemistry-organized at T.J.P.S. College, Guntur - 22nd December 2006.
Research Publications:
  1. An Investigation into phytochemical constituents, antioxidant, antibacterial and anti-cataract activity of Alternanthera sessilis, a predominant wild leafy vegetable of South India. Sobha Kota, Vayunandana Rao Govada, Ratna Kumari Anantha, Mahendra Kumar Verma (2017). Biocatalysis and Agricultural Biotechnology (Elsevier). Available online 15 March 2017, click here
  2. Removal of lead by Adsorption with the renewable biopolymer composite of Feather (Dromaius novaehollandiae) and Chitosan (Agaricus bisporus). Anantha Ratna Kumari and Kota Sobha (2016). Environmental Technology and Innovation (Elsevier), 6: 11-26. (IF - 0.171).
  3. An evaluation of the major factors influencing the removal of copper ions using the egg shell (Dromaius novaehollandiae): chitosan (Agaricus bisporus) biocomposite. RK Anantha and S. Kota (2016). 3 Biotech (Springer), 6: 83. (IF - 0.992).
  4. Optimization and Modeling of Physico-chemical factors affecting the removal of copper from aqueous solutions using feathers of Dromaius novaehollandiae. A. Ratna Kumari and K.Sobha (2015). Journal of Chemical and Pharmaceutical Research, volume 7(7): 449-461. (IF - 0.35)
  5. "Cost effective and eco-friendly method for copper removal by adsorption with Emu feather (Dromaius novaehollandiae) and Chitosan (Agaricus bisporus) Composite". A. Ratna Kumari and K. Sobha (2015). International Journal of ChemTech Research 8(4):1769-1782. (IF - 0.598)
  6. "Utilization of Emu (Dromaius novaehollandiae) Feathers for the Adsorption of Lead from Aqueous Solution: Kinetic, Isotherm and Thermodynamic Studies". Ratna Kumari A, Sobha K (2015). Research Journal of Pharmaceutical, Biological and Chemical Sciences, 6(5):522-532. (IF - 0.35)
  7. "Understanding the major risk factors in the beginning and the progression of rheumatoid arthritis: current scenario and future prospects. Mahendra Kumar Verma and Kota Sobha (2015). Inflammation Research (Springer), 64 (9), 647-659. (IF - 2.557)
  8. Statistical optimization of physico-chemical factors affecting lipase production from A. japonicus cultured in protein enriched medium. K. Sobha, N. Lalitha, N. Pavani, R. Praharshini, D. Pradeep and Mahendra Kumar Verma (2014). Int. J. ChemTech. Res., 6(11), pp. 4817-4831.(IF - 0.598)
  9. Evaluation of Amino acid composition of Phaseolus mungo (Black gram) and Labeo rohita (Rohu) in the perspective of Human dietary requirements. K. Sobha and T. Anita Susan (July-August, 2014). Res J Pharm Biol Chem Sci., Vol. 5 (4), pp. 543-549.
  10. Evaluation of Lipase production from A. japonicus using various vegetable oil substrates and physic-chemical factors affecting lipase activity by Response Surface Methodology. K. Sobha, N. Lalitha, A. Ratna Kumari, K.V. Rajesh and Mahendra Kumar Verma (June, 2014). International Journal of innovative Research in Science, Engineering and Technology, Vol. 3(6), pp. 13610-13621.
  11. Evaluation of cytotoxic and anti-tumor activity of partially purified serine protease isolate from the Indian earthworm Pheretima posthuma. Mahendra Kumar Verma, Francies Xavier, Yogendra Kumar Verma, Kota Sobha (November 2013). Asian Pacific Journal of Tropical Biomedicine, 3(11), pp. 896-901. http://www.ncbi.nlm.nih.gov/pmc/issues/228284/ PMCID: PMC3793163.
  12. Antioxidant and Anti-inflammatory properties of the Autolysed extract of the Indian Earthworm Pheretima posthuma after preliminary purification - an In Vitro study. Mahendra Kumar Verma and Kota Sobha (October - December, 2013). Res J Pharm Biol Chem Sci., 4(4), pp. 888-898.
  13. Nanobiotechnology as a prospective approach for safe environmental remediation - A review A. Ratna kumari and K. Sobha (October 2013). Int J Pharm Bio Sci ., 4(4), pp. 69 - 95.
  14. "Current Prospects of Nano-designs in Gene delivery - Aiming New High For Efficient and Targeted Gene Delivery". M. K. Verma, Y.K. Verma, K. Sobha, Subrato Kumar Dey (October 2013). International Journal of Biopharmaceutics, Vol. 4(3), pp. 145-165.
  15. "L-Asparaginase from Microbes: A Comprehensive Review". D. Santhosh Kumar and K. Sobha (December 2012). Journal of Advances in BioResearch, Vol. 3 (4), pp. 137-157.
  16. "Molecular characterization of bacteria Capable of organophosphate Degradation". A. Ratna Kumari, K Sobha, K Mounika, G J Nageswara Rao and M Ashok (2012). International Journal of Life Sciences, Biotechnology and Pharmacy, Vol. 1 (3), pp. 64-72.
  17. "Biosorption of Cu2+ using animal polymers: chick and duck feathers". A. Ratna Kumari and K. Sobha (April-June, 2012). International Journal of Research in Pharmaceutical and Biomedical Sciences, Vol. 3(2), pp. 664-669.
  18. "Toxicity & Histopathological Changes in the three Indian major carps, Labeo rohita (Hamilton), Catla Catla (Hamilton) And Cirrhinus Mrigala (Hamilton) Exposed To Fenvalerate. T. Anita Susan, K. Sobha, K.S. Tilak. (2012). International Journal of Plant, Animal and Environmental Sciences. Vol. 2 (1), pp. 18-32.
  19. "Red gram Husk - an inexpensive substrate for optimization & production of alkaline protease by Streptomyces griseus (4734) in solid-state fermentation". A. Ratnakumari, Anusha Manne, K.Sobha (2011). Journal of applied Biosciences, 105-109, Vol. 37(2), December, 2011.
  20. "Optimizationof Lead Adsorption Using Animal Biopolymers by Factorial Design", A. Ratnakumari, U. KiranBabu, K.Sobha (2011). International Journal of Science Innovations and Discoveries ( IJSID), Vol. 1 (3), pp. 303-319.
  21. "Biological treatment of the sewage waste water by Immobilized Anaerobic Digester under mesophilic conditions". Meena Vangalapati, Seema Chaitanya Chippada, Sumanjali Avanigadda, Sobha Kota, Padmavathi Veernala (2011). International Journal of Bioengineering, Sciences and Technology, Vol. 2 (3), pp. 63-65.
  22. " A Preliminary Study on Bacteriological Profile of Surgical Wounds". K. Sobha, P. Sarvani, G. Krishna Murthy(2011). Current Trends in Biotechnology and Pharmacy, Vol. 5 (4), pp. 1454-1461.
  23. "Assay of Megesterol acetate by new spectrophotometric method in Pharmaceutical dosage form". A. Ratna Kumari, A. Rajeswari and K. Sobha (2010). Journal of Pharmaceutical Technology and Research, Vol.1(1), pp. 69-71.
  24. " A Comparative study of Kinetics of Itaconic acid production using four species of the genus Aspergillus ". V. Meena, K. Sobha, KRS Sambasiva Rao and KM Subbarathinam (2010). International Journal of Genetic Engineering and Biotechnology, Vol. 1 (3), pp. 165-175.
  25. "Studies on Biochemical Changes in the tissues of Labeo rohita and Cirrhinus mrigala exposed To Fenvalerate Technical Grade". T. Anita Susan, K. Sobha, K. Veeraiah, K.S. Tilak ( October 2010). Journal of Toxicology and Environmental Health Sciences, Vol. 2(5), pp. 53-62.
  26. "Production and Activity Analysis of a Synthetic Cationic Antimicrobial Peptide Expressed from E.coli BL21 (DE3)". P. Jawahar Babu, K. Sobha, K.K. Pulicherla, K.V. Rajesh, K. Venkatesh, G. Harsha and R. Nelson (2010). Journal of Developmental Microbiology and Molecular Biology, Vol. 1 (1), pp. 65-73.
  27. "A Comparative Study on Neurosecretory Control of Courtship-Mating in the two sexes of the Scorption, Heterometrus fulvipes (Koch)". K. Sobha (2010). ANU Journal of Natural Sciences, Vol. 2(1), pp. 63-68. (ISSN No. 09759573).
  28. "Optimization of Hyaluronic Acid Production from Streptococcus equi sub Sps., Zooepidemicus using using Taguchi Design". K.V. Rajesh, K. Sobha, KK Pulicherla, P. Jawahar Babu, K. Venkatesh (2010). International Journal of Biotechnology and Bioengineering Research, Vol. 1(2), pp. 161-170.
  29. "A specific and sensitive assay for Gefitinib using methods in pharmaceutical dosage forms". A. Ratna Kumari, A. Rajeswari and K. Sobha (2010). PHARMANEST, Vol. 1 (1), September - October, pp. 118-122. (ISSN Number 0976 - 3090).
  30. "A study on acute toxicity , oxygen consumption and behavioural changes in the three major Carps, Labeo rohita (ham), Catla catla (ham) and Cirrhinus mrigala (ham) exposed to Fenvalerate". T. Anita Susan, K. Sobha, K. S. Tilak (2010). BioResearchBulletin, Vol. (1), pp. 33-40.
  31. "Emerging Trends in Nanobiotechnology" - Standard Review. K. Sobha, K. Surendranath, V. Meena, T. Keerthi Jwala, N. Swetha and KSM Latha (2010). Biotechnology and Molecular Biology Reviews, Vol. 4(1), pp 1-12.
  32. "Is Protein Structure Prediction Still An Enigma? A Review". K. Sobha, C. Kanakaraju and K. Siva Krishna Yadav. African Journal of Biotechnology. Vol.7 (25), 2008, pp. 4687-4693.
  33. "Haematological parameters as an index of immune response in the heavy metal toxicant induced fish, Catla catla and Labeo rohita (Hamilton)". K. Sobha, N. Siva Prathyush, J. of Eco Toxicology and Environmental monitoring", Vol. 18(6), 2008, 629-634.
  34. "A preliminary study of the histochemical nature of neurosecretory material in different neurosecretory cell groups of the Heterometrus fulvipes (Koch) scorpion" K Sobha, V Kotturu, GR Nagalla, VL Das. Braz. J. Morphol. Sci, 2007; 24(4), 203-207.
  35. "A Cytological study of Neurosecretory cells in relation to Daily rhythm in the scorpion, Heterometrus fulvipes (Koch)". Sobha K, K. Veeraiah & N. Gopala Rao. Indian J. Comp. Animal Physiol., 2007: Vol. 25(1), pp. 10-19.
  36. "Cytological study of Neurosecretion in relation to reproduction in the male scorpion, Heterometrus fulvipes (Koch)". Sobha K, Veeraiah K and Gopala Rao N. Braz. J. Morphol. Sci., 2007: 24(2), pp. 77-87.
  37. "A Study on Biochemical changes in the fresh water fish, Catla catla (Hamilton) exposed to the heavy metal toxicant, Cadmium chloride". Sobha K, Poornima A, Harini P and Veeraiah K. Kathmandu University Journal of Science, Engineering & Technology(KUSET). Vol. 1, No. IV, August, 2007.(e-journal).
  38. "Neurosecretion in relation to reproduction in the female scorpion, Heterometrus fulvipes (Koch)". Sobha K, K. Veeraiah & N. Gopala Rao. Indian Journal of Comparative Animal Physiology, Vol. 24(2), 2006. Pp. 84-91.
  39. "Molecular Characterization of Clotting factors in Crustaceans - A Review". Sobha K., K. Veeraiah, V. Murugan and N. Gopala Rao. J. of Aquatic Biology, Vol.21 (2), 2006, pp. 186-195.

(National: 05 International: 34)


Book/Book Chapter(s) Authored:
  • K. Sobha and D. Santhosh Kumar - Chapter on "Marine Biomaterials: Role in Drug delivery and Tissue Engineering toward Biomedical applications", April 2013, pp. 633 - 656, CRC Press, Taylor and Francis Group. ISBN: 978-1-4665-0564.
  • K. Sobha and D. Santhosh Kumar - Chapter on "Chemistry and Biology of Marine Sponge Collagens". In: Marine Sponges: Chemicobiological and Biomedical Applications, pp. 359-372. Springer Nature, Springer (India) Pvt. Ltd. ISBN 978-81-322-2792-2; . ISBN 978-81-322-2794-6 (eBook) DOI 10.1007/978-81-322-2794-6.
Memberships:
  1. Life member of the Indian Society for Comparative Animal Physiologists (ISCAP)
  2. Life member of Association of Biotechnology and Pharmacy (ABAP)
  3. Life member of the Indian Society for Technical Education (ISTE)
  4. Member of the European Federation of Biotechnology (EFB)
  5. Member, Board of Studies, ANU for UG courses.
  6. Member Secretary, Institutional Ethical Committee, RVR & JCCE.
  7. Member, IBSC - DBT.
Guest Lectures delivered:
  1. "Changing trends in tutor-taught interactions" for young faculty members under Induction Training Program organized by ISTE faculty chapter of RVR & JC College of Engineering on 2nd May, 2015.
  2. "Instructional Objectives and Methodology of Teaching" for young faculty members under Induction Training Program organized by ISTE faculty chapter of RVR & JC College of Engineering on 6th September, 2011.
  3. "Recombinant DNA Technology - Cloning Vectors" - Lecture delivered for the faculty of A.C. College, Guntur, 19th June 2009.
  4. " DNA and its way to Protein" - Lecture delivered for the benefit of students of B.Sc. (Microbiology) and B.Sc. (Biochemistry) at Bapatla College of Arts and Science in November 2006.
Research Guidance:
  1. Registered as a Research Guide in Life Sciences under Periyar University (PRIDE) and Bharathidasan University.
  2. Registered as Research Guide in Biotechnology at Acharya Nagarjuna University and presently guiding five research scholars.
Research Submissions:
  1. Mrs. A. Ratna Kumari submitted thesis entitled "Kinetic, isotherm, and thermodynamic studies on sorption of lead and copper by egg shells and feathers of emu and chick, and their chitosan composites" to Acharya Nagarjuna University for the award of the degree of Doctor of Philosophy in Biotechnology on 15th September 2016.
Research Project Sanctioned:
  1. UGC minor research project for a sum of Rs. 1,85,000/- (One lakh eighty five thousand only) was sanctioned for the work entitled " Purification and Proteomics of thermotolerant lipase isolated from Aspergillus sps. infesting oil seeds" in the month of October 2016. (Proposal number: 3026).
Contact Details:
Phone No. +919491073317; 9985640105

Email: ksobha@rvrjc.ac.in
sobhakota2005@gmail.com